The Role of Myo-Inositol in the Management of Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age, characterized by insulin resistance, hyperandrogenism, and ovulatory dysfunction. Lifestyle modifications, pharmacological interventions, and nutritional supplements play a role in its management. Among these, myo-inositol (MI), a naturally occurring carbohydrate, has gained significant attention for its potential benefits in PCOS management. Understanding Myo-Inositol and Its Role in PCOS Myo-inositol is a stereoisomer of inositol, a component of the B-vitamin complex, and is involved in cell signaling, insulin sensitivity, and ovarian function. It acts as a second messenger in insulin signaling pathways, enhancing glucose uptake and reducing insulin resistance—key factors in PCOS pathology (Pastore et al., 2020). Wom...